Vincent J Pompili MD. FACC, FSCAI, SVP, Novant Health
As cardio-vascular doctors, we are strivingdiligently to address the associated complications and death from cardiac disease. A large population of patients in the U.S. who succumb to heart failure. Cardiac transplantation is an option but we are limited by the number of heart donors who are available in the U.S. Being an interventional cardiologist myself, I know that an individual’s failing heart and vascular health is on top priority and requires periodic monitoring, high-quality diagnosis,and treatment. Several devices and drugs are beingdeveloped in order to reduce the heart associated fatalities.
The Technology Intervention
From a technology standpoint, the evolution and development of neoteric technologies like trans-catheter valves, drug-eluting stents, implanted stimulators, and ICDs have revolutionized the cardiac healthcare sector. While developing and marketing healthcare products, there are standards on which the products are categorized. Simple products like internal pacemakersare abundantly available in the market and can be purchased from different vendors. While complex products like trans-catheter valves, drug-eluting stents,and implanted stimulatorsare developed by a few market leaders and these developers control the purchase price of those products. For patients suffering from critical ailments like generic lipid disorder, costly drugs and devices like PK inhibitors are required to cure the disease. The cost of every drug associated with heart failures has however sky-rocketed. In order to address the pricing predicament, 80 percent of the pharmaceutical establishments are undertaking initiatives to providepatients with cheaper drugs.
"The evolution and development of next generation of technologies like trans-catheter valves, drug-eluting stents, implanted stimulators, and ICDs have revolutionized the cardiac healthcare sector"
Owing to certain regulations exercised by FDA, the U.S. healthcare industry was lagging behind other healthcare industries around the globe in terms of developing and adopting latest technologies. Although past few years were not entirely pervasive in terms of adopting latest technologies, FDA has now become agile in its functionalities paving the way for developers to evolve latest technologies and revamp the health-care facilities.
Innovations in Cardiovascular Care
Today, for instance, the trans-catheter valves help patients tackle the inoperable severe aortic stenosis. By using the valve to treat patients, we brought down the mortality ratio from a staggering 50 percent to less than 20 percent. Having achievedsubstantial positive results from theapplication of TAVR devicetherapy, we are now taking leaps towards micro-valve replacement. It is more complicated in terms of the technology development as the anatomy position of the micro-valve is not direct from an engineering perspective. Furthermore, we are also continuing our research with inter coronary stenting. For patients having severe coronary obstructions,wefollow a procedure where we approach from the patient’s wrist and place a catheterto their heart in order to completely open 3 to 4 blocks in the blood vessels. The process is fast and better than open-heart surgery as the patient gets discharged on the same day or the next day of the treatment process.
Another area of technology that I have been deeply involved in terms of research is the field of cardiovascular regenerative medicine. In this sector, we leverage tissue engineering and plant stem cell cardiomyocytes in patchesand finally apply the patch to the heart in order to improve contractibility.Also, from an electro-physiologic perspective, leadless pacemakers are to be launched in the market soon. Research on developing and deploying leadless pacemakers and implantable cardioverter defibrillatorsthat can be placed through the venal system are underway. We have definitely come a long way with a diverse array of devices and drugs to positively impact on quality of life.
Amanda Reed, Director of Operations for Mednow, Spectrum Health There’s tremendous opportunity for mobile health to provide increased support and connections for patients in between doctor appointments, as well as to help them improve their health-related behaviors and health outcomes overall